Animal-Free Bacterial Endotoxin Testing
The Road to Recombinant Reagents





Michael Parlby – Cormica
Michael Parlby has several years experience in microbiology and is our subject matter expert for the Bacterial endotoxing Testing at Cormica

Animal-Free Bacterial Endotoxin Testing The Road to Recombinant Reagents

Pioneering the Future of Endotoxin Testing: Embracing Recombinant Reagents

Welcome to a pivotal moment in the history of bacterial endotoxin testing. Cormica, as a leading provider of testing services, is at the forefront of revolutionizing this field with our focus on animal-free reagents. Our latest article, “The Road to Recombinant Reagents,” authored by our Business Development Manager, Michael Parlby, marks a significant step in this journey.

Understanding Endotoxins: The Foundation of Our Progress

In our comprehensive article, we delve into the intricate world of endotoxins. We explore their relationship with pyrogens and the evolving definition of endotoxin itself, shedding light on how our understanding of these elements has shaped current testing methodologies.

The Historical Perspective: From Rabbits to Horseshoe Crabs

Tracing the path from the early Rabbit Pyrogen Test (RPT) to the revolutionary use of Horseshoe Crab blood in Limulus Amoebocyte Lysate (LAL), our article takes you through the critical milestones in endotoxin testing. We highlight the ethical and scientific advancements that have paved the way for more humane and precise testing methods.

Recombinant Technology: The Dawn of a New Era

The article illuminates the groundbreaking developments in recombinant DNA technology, showcasing how this innovation led to the first animal-free reagent for bacterial endotoxin testing – a monumental leap towards ethical and efficient testing.

Join Us on This Transformative Journey

As Cormica leads the transition to recombinant reagents, we invite you to stay informed and engaged. 

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