Monocyte Activation Test (MAT)
Broad-Spectrum Pyrogen Detection Using Human Immune Response
Cormica offers Monocyte Activation Testing (MAT) as a robust, human-relevant method for the detection of pyrogens in pharmaceutical products, medical devices and combination products. Using primary human monocytes, MAT enables accurate detection of both endotoxin and non-endotoxin pyrogens, supporting product safety from early development through to final release.
Our MAT Services Include
- Feasibility assessments and method development
- Quantitative and qualitative MAT formats
- Routine batch release testing
- Validation in accordance with regulatory expectations
- Custom study designs tailored to product type and route of administration
Tested to International Standards
MAT testing is performed under:
- European Pharmacopoeia (Ph. Eur.) 2.6.30
- ISO 10993-11 where applicable
